There is no “approved” amyloidosis treatment at this time anywhere in the world to stop the production of the abnormal protein amyloid, which deposits in the organs and tissues in all type of amyloidosis.
In AL present treatments have been borrowed from those which have been shown to work in myeloma, also a bone marrow disease. If the treatment reduces the production of the “light chains” there is a chance that organs and tissues affected by the amyloid may improve.
In AA amyloidosis if the underlying inflammatory disease is successfully controlled the production of the amyloid protein SAA may eventually reduce slowly improving organ function.
In ATTRv and ATTRwt a number of treatments are being trialed to stop the production of the protein in the liver and to stabilize the protein TTR in the blood. At this stage TTR stabilizing drugs have been introduced to therapy but these are not available in Australia as yet.
Consider reviewing the individual types of amyloidosis under the Patient and Carers menu heading above.